
St. John's Wort, An Herbal Remedy For Depression
St. John’s Wort (Hypericum perforatum) is a herbaceous perennial grows 1 to 3 feet tall in uncultivated ground, woods, along hedges and roads and in meadows.
The herb has been used medicinally for centuries. In ancient Greece, the early physicians Galen and Dioscorides recommended Hypericum perforatum as a diuretic, wound healing herb and treatment for menstrual disorders. Interestingly, the name Hypericum perforatum is derived from Greek meaning “over an apparition” and refers to its supposed power to ward off evil spirits.
Contemporary herbalists most often suggest St. John’s Wort for the treatment of mild to moderate depression, and it is widely and safely used for that purpose. The herbal remedy had fewer side effects than prescription antidepressants, and research has shown it safe and effective for the long-term treatment of moderate depression. St. John’s wort contains hypericin, which inhibits monoamine oxidase, a bodily chemical that is associated with depression. It also appears to have a positive impact on the levels of neurotransmitters dopamine, norepinephrine and serotonin, which results in mood elevation.
There are many over the counter St. John’s supplements available. Preparation strength varies widely, so it is important to read the labels. For minor depression, 300 milligrams of active ingredient should be sufficient to moderate depression at least 900 milligrams a day are needed to achieve an effect. Preparations from supermarkets and drug stores usually contain a significantly smaller amount of active ingredient. The same applies to tea preparations. The effect is felt only after about three weeks. One lasting impact is even only after four to six months.
As with any therapeutic agent, caution is needed. The active agents of the St. John’s Wort is metabolized by the liver, and there may be interactions with other drugs (for example, blood-thinning medications, some antibiotics, beta blockers, fat-lowering agents, cortisone, epilepsy drugs, and cytostatics and sedatives). Another side effect, light sensitivity of the skin, has been observed. This side effect is reinforced by the simultaneous intake of birth control pills.
(Also known as St. John’s Wart)